Chet L. Nastala, M.D., FACS

Current Practice                 

PRMA 

Plastic, Reconstructive, and Microsurgical Associates of South Texas

Attending Plastic Surgeon, Methodist Healthcare System

Biographical

BIRTHDATE:               

August 23, 1963

BIRTHPLACE:                  

Philadelphia, PA

SPOUSE:                            

Carla Jane Nastala, R.N., M.S.N.       

Education and Training

UNDERGRADUATE

1981-1985                           

Harvard University: College of Arts and Sciences, Cambridge, MA

Bachelor of Arts, 1985                        

Biochemical Sciences                           

magna cum laude

GRADUATE

1985-1989                           

Duke University: School of Medicine, Durham, NC

Doctor of Medicine, 1989    

Kenneth Pickrell Scholarship

POST GRADUATE

1989-1992                           

University of Pittsburgh Medical Center, Pittsburgh, PA             

Richard L. Simmons, M.D.

Chairman, Dept of Surgery

GMT I, II, III - Intern/ Resident in General Surgery

1992-1994                           

University of Pittsburgh Medical Center Pittsburgh, PA                                      

Michael T. Lotze, M.D., Director, Surgical Oncology

Howard D. Edington, M.D. Plastic Surgical Oncology

Surgical Oncology and  Surgical Research Fellowship

1994-1996                           

University of Pittsburgh Medical Center, Pittsburgh, PA

Richard L. Simmons, M.D.

Chairman, Dept of Surgery

GMT IV-V, Chief Resident in General Surgery

1996-1998                           

University of Pittsburgh Medical Center,  Pittsburgh, PA

J. William Futrell, M.D.

Chief,  Plastic Surgery

GMT VI-VII, Plastic Surgery Residency

Academic Appointments

7/2002                                 

Private Practice, Plastic and Reconstructive Surgery

Plastic, Reconstructive and Microsurgical Associates of South Texas

7/2001                                 

Chief, Plastic and Reconstructive Surgery

University of Texas Health Science Center San Antonio

1/2001                                 

Program Director,  Plastic Surgery Residency

Interim Chief, Plastic and Reconstructive Surgery

University of Texas Health Science Center San Antonio

2000                                    

Associate Program Director, Plastic Surgery Residency

University of Texas Health Science Center San Antonio

1999                                    

University of Texas Health Science Center San Antonio

Director of Graduate and Student Education in Plastic Surgery

1998                                    

University of Texas Health Science Center San Antonio

Assistant Professor of Plastic Surgery

Chief, Section of Aesthetic and Reconstructive Breast Surgery

Board Certification 

1999                                    

American Board of Surgery

Certified February 1999, renewal 7/1/2009

1999                                    

American Board of Plastic Surgery

Certified September 1999, renewal 9/18/2009

Medical Staff Appointments 

2001                                    

Southwest Texas Methodist Hospital System

Plastic and Reconstructive Surgery

San Antonio, TX

2001                                    

University Health System

Chief, Plastic and Reconstructive Surgery

San Antonio, TX

1999                                    

Baptist Health Network

San Antonio, TX

Attending Plastic Surgeon

1999                                    

Christus Santa Rosa Health Care System

Attending Plastic Surgeon

San Antonio, TX

1999                                    

Audie L Murphy Veterans Administration Hospital

Chief, Section of Plastic Surgery

San Antonio, TX

1998                                    

Audie L Murphy Veterans Administration Hospital

Director of Plastic Surgical Services

San Antonio, TX

1998

University Health System

Attending Plastic Surgeon

San Antonio, TX

Professional Societies

American Society of Plastic Surgeons

American Society of Plastic and Reconstructive Microsurgery

American College of Surgeons

Texas Society of Plastic Surgeons

Texas Medical Society

San Antonio International Society of Plastic Surgeons

Bexar County Medical Society

University of Pittsburgh Plastic Surgery Society

Licensure

1990 Pennsylvania State License                               

1991 Federal Drug Enforcement Agency

1992 Laser Certification,  University of Pittsburgh

1993 Emergency Medical Command Certification 

1993 Advanced Trauma Life Support

1993 Advanced Cardiac Life Support

1994 Laser Re-Certification, University of Pittsburgh

1995 Laser Re-Certification, University of Pittsburgh

1998 Texas State License

1998 Texas Department of Public Safety                   

Committees

2000-2002                              

Young Plastic Surgeons Committee                                          

American Society of Plastic Surgery

2000-2002                              

Utilization Review Committee                                       

University Health System                                             

San Antonio, TX

2000-2002                              

Chairman, Laser Committee                                         

University Health System                                             

San Antonio, TX

1999-2001                              

Operating Room Committee

University Health System

San Antonio, TX

1999-2001                              

UTHSCSA Cancer Committee

University of Texas Health Science Center San Antonio

1999                                       

Laboratory Animal Services Resource Utilization

Department of Surgery

University of Texas Health Science Center San Antonio

1999                                       

Oral Maxillofacial Surgery Chair Search Committee

University of Texas Health Science Center San Antonio

Honors and Awards

1981-1985                              

Magna cum laude

Ada Howe Kent Scholar

Harvard College Scholarship

1985-1989                              

Dr. Kenneth L. Pickrell Scholarship

Duke University School of Medicine

1996                           

Mark Ravitch Teaching Award – Surgery

1997                                       

Charles C. Moore School of Medicine Teaching Award - Surgery

2000                                       

Outstanding Educator Award – Division of Plastic Surgery

UT Health Science Center, San Antonio

Publications

REFEREED ARTICLES

Kresh, J.Y., Nastala, C.L., Bianchi, P.C., Goldman, S.M., Brockman, S.K.  The relative buffering power of cardioplegic solutions.  The Journal of Thoracic and Cardiovascular Surgery 1987; 93(2): 309-311.

Tyler, D.S., Nastala, C.L., Lyerly, H.K., Matthews, T.J., Bolognesi, D.P., Weinhold, K.J.  Direct ADCC:  Evidence for circulating antibody armed cytotoxic CD16+ NK/K cells in patients infected with HIV-1.  Surgical Forum 1988; 418-420.

Prince, A.F., Horowitz, B., Baker, L., Schulman, R.W., Ralph, H., Valinsky, J., Cundell, A., Brotman, B., Boehle, W., Rey, F., Piet, M., Reesink, H., Lelie, N., Tersmette, M., Miedems, F., Barbosa, L., Nemo, G., Nastala, C.L., Allan, J.S., Lee, D.R., Eichberg, J.W.  Failure of a human immunodeficiency virus (HIV) immune globulin to protect chimpanzees against experimental challenge with HIV.  Proc Natl Acad Sci 1988; 85: 6944-6949.

Lyerly, H.K., Skinner, M.A., Tyler, D.S., Nastala, C.L., Matthews, T.J., Bolognesi, D.P., Weinhold, K.J.,  Anti-HIV immune cytolysis is independent of viral envelope glycosylation.  Surgical Forum 1988; 420-422.

Tyler, D.S., Nastala, C.L., Stanley, D.S., Matthews, T.J., Lyerly, H.K., Bolognesi, D.P., Weinhold, K.J.  GP120 Specific cellular cytotoxicity in HIV-1 seropositive individuals:  Evidence for circulating CD16 positive effector cells armed in vivo with cytophilic antibody.  Journal of Immunology 1989; 142: 1177-1182.

Tyler, D.S., Lyerly, H.K., Nastala, C.L., Shadduck, P.P., Fitzpatrick, K.T., Langlois, A.J., Moylan, J.A.  Barrier protection against the human immunodeficiency virus.  Current Surgery 1989; 46: 301-304.

Tyler, D.S., Stanley, S.D., Nastala, C.L., Austin, A.A., Bartlett, J.A., Stine, K.C., Lyerly, H.K., Bolognesi, D.P., Weinhold, K.J.  Alterations in antibody dependent cellular cytotoxicity during the course of HIV-1 infection.  Humoral and cellular defects.  Journal of Immunology 1990; 144: 3375-3384.

Nastala, C.L., Edington  H., Storkus, W.J., and M.T. Lotze.  Recombinant Interleukin-12 (r-mIL-12) mediates regression of both subcutaneous and metastatic murine tumors.  Surgical Forum 1993; 44: 518-521.

Nastala, C.L., McKinney, T., Edington  H., Tahara, H., Gately, M.K, Storkus, W.J., and M. T. Lotze.  Interleukin-12 (IL-12) induces specific anti-tumor immunity in animals bearing established subcutaneous murine sarcoma.  Surgical Forum 1994; 45.

Hoehnke, C., Nastala, C.L., Tahara, H., Suzuki, T., Edington, H. and M.T. Lotze.  The use of gene transfer of viral IL-10 to facilitate allogeneic skin transplantation.  Surgical Forum. 1994; 45.

Nastala, C.L., Edington  H., McKinney, T.G., Tahara, H., Brunda, M., Gately, M., Wolf, S., Hubbard, B., and M.T. Lotze. Recombinant interleukin-12 (IL-12) administration induces tumor regression in association with interferon-gamma production. Journal of Immunology 1994; 153: 1697-706.

Matthes, G, Zabel, D. D., Nastala, C.L., Shestak, K.C.  Endometrioma of the abdominal wall following combined abdominoplasty and hysterectomy: Case report and review of the literature. Annals of Plastic Surgery 40(6):672-5,1998.

Nastala, C.L.,  Techniques in Perineal Reconstruction.  eMedicine, emedicine.com 2001 (online journal, peer reviewed)

Nelluri, P.K., Lyons,R.C.., Nastala, C.L., Garza, J.R..  Functional Assessment of the sciatic nerve after repair with local delivery of FK506 in rats.  Canadian Journal of Plastic Surgery, Vol 10 No x March 2002.

Leong K, Nastala CL, Wang PT. Cosmetic aspects of cranial reconstruction.
Neurosurg Clin N Am. 2002 Oct;13(4):491-503, vi.

Pisano, S.P., Ledoux., Nastala, C.L.  Breast Reconstruction in Private Practice.  A New Decade in Breast Reconstruction.  Saleh Shenaq., MD.ed  Seminars in Plastic Surgery Vol 18 No 2, 2004.

Nastala, C.L., Lyons, R, Kim, B., Massive facial edema following neck dissection and its treatment with multimodal therapy.

Books and Chapters

Weinhold, K.J., Lyerly, H.K., Matthews, T.J., Tyler, D.S., Nastala, C.L., and D.P. Bolognesi. Specific cell-mediated cytotoxicity against HIV-1 envelope glycoprotein coated CD4 cells. in Autoimmune aspects of HIV infection, Andrieu, J.M., Bach, J.F., and P. Even, eds.  Royal Society of Medicine, London 143-151, 1988.

Matthews, T.J., Rusche, J.R., Skinner, M., Putney, S.D., Lyerly, H.K., Nastala, C.L., Tyler, D.S., Weinhold, K.J., and Bolognesi, D.P.  Immunology of the external envelope viral glycoprotein.  in AIDS and associated cancers in Africa,  Giraldo, G., Giraldo, E., Clumeck, N., Gharbi, M., Kyalwazi, S., and Guy de The, eds. Karger, Basel 237-245, 1988.

Tyler, D.S., Stanley, S.D., Nastala, C.L., Lyerly, H.K., Matthews, T.J., Bolognesi, D.P., and Weinhold, K.J.  Antibody-directed Anti-HIV-1 Cellular Cytotoxicity:  Role of NK/K cells armed with gp120-specific antibodies in therapeutic and vaccine strategies.  in Vaccines 89: New Chemical and Genetic Approaches to Vaccination, Prevention of AIDS and other Viral Bacterial, and Parasitic Diseases,  Ginsberg, H., Brown, F., Lerner, R.A., and R.M. Chanock, eds.  Cold Spring Harbor Laboratory, 155-158, 1989.

Lyerly, H.K., Tyler, D.S, Nastala, C.L., and K.J. Weinhold.  Anti-HIV-1 ACDD. in AIDS Vaccine Research and Clinical Trials,  Putney, S.D. and Bolognesi, D.P. eds.  Marcel Dekker, Inc. New York 157-177, 1990.

Freeswick, P.D., Nastala, C.L., and T.R.Billiar.  Molecular Mechanisms of Hepatic Failure.  R.G. Landes Co. ISBN 1570590982, Dec 1995

Nastala, C.L., McCraw, J.B., and A. McMellin. Vaginal Reconstruction using the Gracilis Myocutaneous Flap. In Reconstructive and Plastic Surgery of the External Genitalia, Gary Alter, ed. W.B.Saunders, Co.  1998.

Nastala, C.L., and K.C. Shestak.  Breast Reconstruction. In Plastic Surgical Secrets, Weinzweig, J. ed.,  Hanley and Belfus, Philadelphia, 254-258, 1999.

Miller, A.R., Chew, H.K., Zellers, R., Nastala, C.L.., and F. Sharkey.  Breast Sarcoma. In Cancer Therapy 2002.

Nastala, C.L., Chrysopoulo, MT, Pisano, SP. Ledoux, P.  Free TRAM Breast Reconstruction in Scott Spear Surgery of the Breast Third Edition.

Pisano, S.M., Ledoux, PR., Nastala, CL, Chrysopoulo, MT.  Breast Reconstruction in Private Practice in a new decade of Breast Reconstruction.  Saleh Shenaq Ed.  Seminars in Plastic Surgery Vol 18 No 2 2004. 

Published Abstracts and Presentations

Nastala, C.L.  Mock circulatory system evaluation of left ventricular assist.  Proceedings of the Annual Conference for Engineering in Medicine and Biology 1984; 37:65.

Kresh, Y., Nastala, C.L., Goldman, S., Fox, D., Brockman, S.  The relative buffering power of cardioplegic solutions.  Faculty of the American Society of Engineering in Biology 1985.

Kresh, J.Y., Nastala, C.L, Goldman, S.M., Fox, D., Brockman, S.K.  Continuous monitoring of intramyocardial pH:  Relative buffering power of cardioplegic solutions.  International Society for Heart Transplantation 1986.

Nastala, C.L., Tyler, D.S., Lyerly, H.K., Matthews, T.J., Bolognesi, D.P., Weinhold, K.J.  Antibody isotypes directing anti-GP120 antibody dependent cell mediated cytotoxicity.  Proceedings of the Fourth International Conference on AIDS, presented in Stockholm, Sweden. 1988; 1:2102.

Tyler, D.S., Nastala, C.L., Stine, K.C., Bartlett, J., Bolognesi, D.P., Lyerly, H.K., Weinhold, K.J.  Therapeutic application of interleukin-2 augmentation of HIV-1 specific cellular immune reactivity.  Proceedings of the Fourth International Conference on AIDS, Stockholm, Sweden. 1988; 2:3524.

Tyler, D.S., Nastala, C.L., Lyerly, H.K., Stanley, D.S., Matthews, T.J., Bolognesi, D.P., Weinhold, K.J.  HIV specific killer cells armed in situ with cytophilic antibodies. Proceedings of the Fourth International Conference on AIDS, Stockholm, Sweden. 1988; 1:2183.

Nastala, C.L., Edington, H., McKinney, T, and M. Lotze.  Immunologic effects of murine interleukin-12 in vitro on human and murine lymphoid cells.  The Society for Biologic Therapy of Cancer, presented in Williamsburg, VA. 1992; 37.

Nastala, C.L. and H. Edington. Clostridium septicum associated with benign and malignant colonic neoplasms and neutropenic enterocolitis.  Surgical Infection Society. presented in Baltimore, MD, 1993.

Nastala, C.L., Edington  H., McKinney, T.G., Tahara, H., Brunda, M., Gately, M., Wolf, S., Hubbard, B., and M.T. Lotze.  Local administration of interleukin-12 blocks in vivo progression of murine adenocarcinoma and sarcoma.  Keystone Symposia, Immunotherapy of Cancer, presented in Taos, NM. Journal of Cellular Biochemistry, supplement 17D, 1993; 134.

Tahara, H., Zeh, H., Pappo, I., Nastala, C.L., Robbins, P.D., and M.T. Lotze.  Tumor growth alteration with local interleukin-12 secretion achieved by gene transfer.  Keystone Symposia on Gene therapy, Keystone, CO.  1993.

Nastala, C.L., Edington  H., Tahara, H., Zeh, H., McKinney, T., and M. T. Lotze. Murine interleukin-12 generates anti-tumor reactivity in vitro against murine tumors.  Society for Surgical Oncology, Los Angeles, CA. 1993.

Tahara, H., Zeh, H., Pappo, I., Nastala, C.L., Robbins, P.D., and M.T. Lotze.  Suppressed growth of murine melanoma in vivo with local secretion of  interleukin-12 delivered by transfected fibroblasts.  Proceedings of the American Association for Cancer Research, Orlando FL. 1993; 34:463. 

Nastala, C.L., Edington  H., Storkus, W.J., and M.T. Lotze.  Recombinant Interleukin-12 (r-mIL-12) mediates regression of both subcutaneous and metastatic murine tumors.  ACS Surgical Forum  San Francisco, CA. 1993; 44: 518-521.

Pappo, I., Tahara, H., Nastala, C.L., Robbins, P.D., Zeh, H., and M.T. Lotze.  Cancer gene therapy with IL-12, alone or in combination with systemic IL-2 administration delays or prevents the growth of murine sarcomas.  Association for Academic Surgery, Hershey, PA 1993. 

Nastala, C.L., McKinney, T., Edington  H., Tahara, H., Gately, M.K, Storkus, W.J., and M. T. Lotze.  Interleukin-12 (IL-12) induces specific anti-tumor immunity in animals bearing established subcutaneous murine sarcoma.  ACS Surgical Forum  Chicago, IL. 1994; 45.

Nastala, C.L., Newton, E.D., Edington, H.D., and K.C. Shestak.  Outcome measures in free flap reconstruction of the foot. Robert H, IVY Society, Philadelphia, PA 3/97

Kessler, R., Nastala, C.L. Breast Hypertrophy and Protease Inhibitors in the HIV Positive patient.  Texas Society of Plastic Surgeons, Barton’s Creek, TX  10/99

Desvigne, L., Nelluri, P., Nastala, C.L., Garza, J.R..  The Aging neck: Central bands are independent of platysma decussation. Senior Res Conference, Providence, RI 3/01

Lyons,R., Nelluri, P., Nastala, C.L., Garza, J.R..  A local drug delivery method to enhance nerve regeneration. Senior Res Conference, Providence, RI 3/01

Nastala, C.L., Pisano, S.M., Ledoux, P.R., Texas Society of Plastic Surgeons, The DIEP Flap in Breast Reconstruction, The Gold Standard?  Hyatt Hill Country, San Antonio TX  9/21/03

Dev, V.R., Ledoux, P.R., Pisano, S.M., Nastala, C.L., American Society of Plastic Surgeons, Innervating the DIEP Flap: Anatomical Considerations to Simplify and Improve Somatosensory function of the Reconstructed Breast.  San Diego California,  10/26/03

Nastala, C.L., Pisano, S.M., Ledoux, P.R., American Society of Reconstructive Microsurgery Surgeons, The DIEP Flap in Breast Reconstruction, Improving the Efficiency of Health Care Delivery. Palm Springs, CA, 1/2004

Pisano, S.M., Ledoux, P.R., Nastala, C.L., American Society of Reconstructive Microsurgery Surgeons, Clinical Course  Performing the DIEP Flap Breast Reconstruction in Private Practice. Tucson AZ, 1/2006

Invited Talks and Lectures

Treatment of Secondary Deformities in Cleft lip and Palate.  Plastic Surgery Grand Rounds, University of Texas Health Science Center at San Antonio 10/1/98

Current Progress in Melanoma.   The San Antonio Surgical Society  10/15/98

Methods of perineal reconstruction.  Plastic Surgery Grand Rounds, University of Texas Health Science Center at San Antonio 1/14/99

The use of the Posterior Thigh Flap in Vaginal Reconstruction.  Society of Air Force Clinical Surgeons.  San Antonio, TX 3/31/99

Management of tendon injuries.  Plastic Surgery Grand Rounds, University of Texas Health Science Center at San Antonio 9/16/99

Breast Hypertrophy and Protease Inhibitors in the HIV Positive patient: The role of the Plastic Surgeon.  Texas Society of Plastic Surgeons, Barton’s Creek, TX  10/8/99

Advances in Wound Care.  San Antonio International Society of Plastic Surgeons, San Antonio, TX  4/2000

Moderator  TexMed 2000; Plastic Surgery Session of the Texas Medical Association, San Antonio, TX 5/25/2000

Skin Sparing Mastectomy and Immediate Breast Reconstruction, State of the Art, TexMed 2000; Texas Medical Association, San Antonio, TX  5/25/2000

Decubitus Ulcers, When in Surgery Appropriate?  Texas Medical Association, TexMed 2000; San Antonio, TX  5/25/2000

Texas Society of Plastic Surgeons, Short Scar Breast Surgery: Is it here to stay?  La Cantera, San Antonio TX  9/21/01

Advanced Concepts in Cosmetic and Reconstructive Breast Surgery.  Plastic Surgery Grand Rounds, University of Texas Health Science Center at San Antonio  2/14/02