A Word of Caution on FDA Approved At-Home Breast Cancer Gene Testing
By: Courtney Floyd
This is an exciting advancement for health empowerment, however before ordering this at-home genetic test there are a few things you should know:
- The test only screens for three specific BRCA1 and BRCA2 mutations out of the 1,000+ known gene mutations that increase the risk for breast cancer. While the detection of a BRCA mutation on this test does indicate an increased risk, only a small population carry one of these three mutations. Most BRCA mutations that increase the risk of cancer are NOT detected with this test.
- This test does NOT substitute evaluation by a doctor and genetic counselor. Although this test is less expensive and perhaps more convenient, the knowledge that comes with these test results is extremely limited and should not be used to make any medical treatment decisions.
“In my opinion, individuals should not have genetic testing without going through counseling from a certified genetic counselor first, so they can have all the information needed to make a fully-informed decision,” said Dr. Chrysopoulo after hearing the news. “For many, learning about a genetic mutation they carry and not knowing the potential implications can be a very difficult situation to navigate. It has implications not just for the patient, but for their entire family (in terms of health-related decision-making, planning, and health and life insurance). As if the former two aren’t enough, the latter can be financially devastating. Individuals should get tested if they want, but counseling ahead of time arms the them with the information they need to truly make the best decision for them. There are far reaching consequences of testing, both intended and unintended, that will be important for many people, but without prior counseling most folks can’t possibly realize what those are until the it’s too late. That’s a big concern for me.”