Prophylactic Mastectomy

Prophylactic mastectomy is a good option for patients who are at high risk of developing breast cancer. In certain situations, prophylactic mastectomy can reduce the risk of developing breast cancer by 90%-95%. 

If any of the following apply to you, you are a candidate for prophylactic mastectomy:

  • a positive test for a genetic mutation that predisposes to breast cancer (eg BRCA1, BRCA2, PALB2, CDH1, PTEN, or TP53)
  • several family members who developed breast cancer (including mother, sister, or daughter), especially before age 50
  • a particularly aggressive or invasive breast cancer
  • high risk histology on biopsy (eg "invasive lobular" disease or "lobular carcinoma in situ")
  • multiple tumors in the same breast
  • very young age at the time of the first breast cancer diagnosis
  • chest radiation before age 30 
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PRMA Plastic Surgery